1. What is the deal with my cleric's religion?
Rockulon Prime is traditionally monotheistic, so you more than likely worship the Space-God. Encompassing everything, you can be of any alignment and worship any of the dead-but-dreaming Space-God's aspects. The nearby planet of Llurb Tdunon allegedly worships Lolth, the Princes of Elemental Evil, and two of the Slaadi Lords, so some few heretics might worship those.
2. Where can we go to buy standard equipment?
Most towns of decent size have general stores, blacksmiths, etc. You likely won't find anywhere that sells everything you need, but the market probably encompasses whatever you'd want. The sample town of Västernorr holds the Bizarre Bazaar, and being close to the borderlands, you can probably find any weird equipment item or piece of scavenged drowtech if you look hard enough.
3. Where can we go to get platemail custom fitted for this monster I just befriended?
Any blacksmith worth his salt could probably custom make armor, particularly in a settlement where mutants are welcome.
4. Who is the mightiest wizard in the land?
He's technically off-world, although still in the planet's orbit, but the demilich known as the Librarian of a Thousand Lunacies probably counts. Doctor of metalphysics and wizardology Karl Satan is probably one of the best known in academic circles. Wiss Khan Sin was fairly potent in his time.
5. Who is the greatest warrior in the land?
Many storied heroes are known to the people of Rockulon Prime, but Midnight Lordzealot allegedly killed Glithuthatu the Putrid, an infamous Hell-Maggot that had long plagued the people of Fórnarlamb.
6. Who is the richest person in the land?
Again, off-planet, but the Librarian of a Thousand Lunacies certainly counts. There's a lot of talk that the monarch of the enlightened city-state of Skarpurlofa holds a great deal of wealth in her coffers, but some folks also say the Cosmic Hierophant of Lok Tooran controls a fair amount of cash garnered from tithes.
7. Where can we go to get some magical healing?
Any major city probably has a temple with a settled cleric of the Space-God. Smaller towns and villages may have a doctor or herbalist who can give you some treatment, even if it's not wholly magical. Some borderlands towns may have access to scavenged drowtech, which might as well be magic.
8. Where can we go to get cures for the following conditions: poison, disease, curse, level drain, lycanthropy, polymorph, alignment change, death, undeath?
Again, a temple can probably help you in a major city, although you may also want to check out a drowtech specialist. Smaller towns have to make do with doctors and herbalists, who very well may not be able to treat any major curses. The fabulous lost technology of the once-great drow might be able to handle that, but again, that depends on finding a mechanic, scavenger, or Grease Monkey with access to lost drowtech.
9. Is there a magic guild my MU belongs to or that I can join in order to get more spells?
The University of Wiss Khan Sin is probably the best known, but there are no doubt other schools and guilds throughout Rockulon Prime.
10. Where can I find an alchemist, sage or other expert NPC?
Major cities and border towns are your best bet. Anywhere with a University of Wiss Khan Sin annex is probably safe.
11. Where can I hire mercenaries?
Any major city-state or border town probably has a mercenary company of notable size.
12. Is there any place on the map where swords are illegal, magic is outlawed or any other notable hassles from Johnny Law?
The whole world is pretty adventure-friendly, although you may have to deal with whatever strange decrees the local leaders have concocted. The Cosmic Hierophant and his Schizoid Parliament of Lok Tooran have some...rather strange local ordinances.
13. Which way to the nearest tavern?
The tavern is the heart of the town, so you're likely close to one.
14. What monsters are terrorizing the countryside sufficiently that if I kill them I will become famous?
Hell-Maggots are so grotesque and feared that they likely count, especially for the larger ones. Individual spots may be plagued by feral mutants, goblins, gnolls, orcs, undead, or whatever local monster is common in the region. Liches tend to be widely feared enough to count. Creatures of the Outside — aboleths, beholders, mind flayers, and suchlike — are also widely feared and hated enough to count.
15. Are there any wars brewing I could go fight?
There's always some pissing contest among city-states. Lok Tooran's Schizoid Parliament tends to instigate conflict with its neighbors. The undead warlord and Dread Warrior known as Seraph Sinner-anger is frequently on the march with his warband, and rumor has it that he can only be stopped by the Axes of Evil of Torturion...
16. How about gladiatorial arenas complete with hard-won glory and fabulous cash prizes?
They're not common, although sizable towns and cities on the frontier likely have them. Any town lacking gladiatorial bouts will likely have unofficial boxing matches or fights if you want to get in the underground fighting circuit.
17. Are there any secret societies with sinister agendas I could join and/or fight?
Since the Space-God encompasses all alignments, his Evil adherents frequently count (although some rule openly). Secret societies tend not to range beyond their own city-states, although there are persistent rumors of a widespread conspiracy of jingoist drow who wish to return to the glories of their decadent and fallen civilization.
18. What is there to eat around here?
Depends on where you go. Prodigious quantities of alcohol are pretty much universal.
19. Any legendary lost treasures I could be looking for?
Well, the Axes of Evil mentioned above likely count. The lost technomagical marvels of the drow are renowned as being fairly potent. Any warlord who could recover an operational Bloodstone Bomb (and not vaporize himself and the surrounding countryside in the process) could probably take any city-state he or she wanted.
20. Where is the nearest dragon or other monster with Type H treasure?
Again, depends on where you are. The now-dead Lord Vau had a lot of treasure stashed in his tower, and there are some dragons overlooking hordes. Some of the older Hell-Maggots rest among hoary tombs with archaic treasure hordes, although the legendary Vakothmm the Tumescent Putrescence allegedly lairs in the hallowed halls of a long-dead drow queen.